Immunocytochemistry at the Electron-Microscopic Level
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Localization of nucleolar chromatin by immunocytochemistry and in situ hybridization at the electron microscopic level.
Nucleoli are the morphological expression of the activity of a defined set of chromosomal segments bearing rRNA genes. The topological distribution and composition of the intranucleolar chromatin as well as the definition of nucleolar structures in which enzymes of the rDNA transcription machinery reside have been investigated in mammalian cells by various immunogold labelling approaches at the...
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تاریخ انتشار 2017